Cyclosporine Treatment of Intractable Colitis in Chronic Granulomatous Disease
نویسندگان
چکیده
منابع مشابه
Colitis in chronic granulomatous disease.
BACKGROUND Involvement of the gut in chronic granulomatous disease (CGD) has been previously described and colitis highlighted. However, the nature and histopathology of the colitis are unclear and have been thought to be non-specific or similar to Crohn's disease. METHODS Seven patients with CGD, suffering from gastrointestinal symptoms were prospectively studied. RESULTS All patients had ...
متن کاملIntractable colitis associated with chronic granulomatous disease in a young girl.
Chronic granulomatous disease (CGD) is an autosomal recessive or X-linked disorder caused by NADPH oxidase deficiency leading to an impaired ability of reactive superoxide anion and metabolite formation and recurring severe bacterial and fungal infections, with a high mortality rate. Diarrhea, colitis, ileus, perirectal abscess formation and anal fissures are reported gastrointestinal findings ...
متن کاملTreatment of chronic granulomatous disease.
From the European Group for Blood and Marrow Transplantation (EBMT) and the European Society for Immunodeficiencies (ESID) 1: Division of Immunology/Hematology, University Children's Hospital, Zurich, Switzerland; 2: Dr. von Haunersches Kinderspital, Ludwig Maximilians University, Munich, Germany; 3: Unité d'Immuno-Hématologie et Service de Biostatistique, Hôpital Necker Enfants Malades, Paris,...
متن کاملulcerative colitis associated with chronic granulomatous disease: case report
chronic granulomatous disease (cgd) is an inherited primary immunodeficiency disease which increases the body’ssusceptibility to infections caused by certain bacteria and fungi. cgd is a rare disease, caused by four genes, one type is 1xlinked and the other three are “autosomal recessive”. although clinical presentation is variable, but characteristic featuresare recurrent pneumonia, lymphadeni...
متن کاملColitis complicating chronic granulomatous disease. A clinicopathological case report.
BACKGROUND This report concerns a female patient now aged 24 years, diagnosed at the age of 7 years as suffering from chronic granulomatous disease. At age 20 she developed diarrhoea accompanied by rectal bleeding. Endoscopy showed extensive colitis. She failed to respond to medical treatment and underwent total colectomy two years later. AIMS To discuss the histological changes in the colon ...
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ژورنال
عنوان ژورنال: Pediatric Asthma, Allergy & Immunology
سال: 2000
ISSN: 0883-1874,1557-7767
DOI: 10.1089/pai.2000.14.125